Lethality of Rw/Rw Mouse Embryos during Early Postimplantation Development
نویسندگان
چکیده
منابع مشابه
Parthenogenetic development of mouse embryos in vivo. II. Postimplantation development.
CBA-p and CBA-T6T6 females were mated with vasectomized males of A strain and early in the morning the eggs were activated in situ with the electric shock of 30, 40 and 50 V. Females were killed between the 5th and the 10th day of pregnancy and the implantation sites were studied histologically or their content was examined under the dissecting microscope. Of the uterine horns, 43-6 % contained...
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The chromosome constitution of early postimplantation presumptive haploid parthenogenetic mouse embryos was examined. All the embryos isolated were at the egg-cylinder stage and seven contained dividing cells. In two of the apparently healthy embryos only haploid mitoses were seen, whereas in five others an approximately equal proportion of haploid and diploid mitoses was observed. Out of 52 ce...
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Hyperthermia (HS) and 4-hydroperoxycyclophosphamide (4CP) activate the mitochondrial apoptotic pathway in day 9 mouse embryos. Previous microarray analyses Microarray analyses revealed that several p53 target genes are upregulated after exposure to HS or 4CP, suggesting a role for p53 in teratogen-induced apoptosis. To explore the role of p53, we assessed the activation of p53 in day 9 mouse em...
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The expression of the intermediate filament (IF) constituents desmin, vimentin and keratin, as well as the striated-muscle-specific marker titin, was studied in mouse embryos of 8.0 to 9.5 days post coitum (d.p.c.), using the indirect immunofluorescence technique in combination with polyclonal and monoclonal antibodies. During the development of the embryo, desmin was first detected at 8.25 d.p...
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Despite the fact that a variety of experimental techniques have been devised over the years to induce tetraploid mammalian embryonic development, success rates to date have been limited. Apart from the early study by Snow, who obtained development to term of a limited number of cytochalasin B-induced tetraploid mouse embryos, no other researchers have achieved development of tetraploid embryos ...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 1995
ISSN: 0012-1606
DOI: 10.1006/dbio.1995.1082